Geriatric Healthcare Specialist Mattapan MA

In a study recently published in the Journal of Alzheimer’s Disease, researchers from Brown Medical School found that reduced glucose uptake and decreased metabolism in the hippocampus—the area of the brain associated with memory—cause neurodegeneration and cognitive impairment.

Evgenia Forman
(617) 296-5100
2216 Dorchester Ave
Dorchester Center, MA
Specialty
Internal Medicine, Geriatric Medicine

Data Provided by:
Roger Schutt
(617) 296-4000
2100 Dorchester Ave
Dorchester Center, MA
Specialty
Geriatric Medicine

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DeBorah A O'Keefe
(617) 296-4000
2100 Dorchester Ave
Dorchester Center, MA
Specialty
Geriatric Medicine

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Susan Cohen Kalish, MD
1200 Centre St
Boston, MA
Specialties
Geriatrics, Geriatric Medicine-Internal Medicine
Gender
Female
Education
Medical School: Cornell Univ Med Coll, New York Ny 10021
Graduation Year: 1988

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Randi Ellen Berkowitz
(617) 325-8000
1200 Centre St
Roslindale, MA
Specialty
Internal Medicine, Geriatric Medicine

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Mark Stephan Ostrem
(617) 296-4012
2100 Dorchester Ave
Dorchester Center, MA
Specialty
Internal Medicine, Geriatric Medicine

Data Provided by:
Chinh Duy Le, MD
1980 Dorchester Ave
Dorchester Center, MA
Specialties
Geriatrics, Geriatric Medicine-Internal Medicine
Gender
Male
Education
Medical School: Med & Pharm Univ, Ho Chi Minh City, Viet Nam (840-01 Prior 1/71)
Graduation Year: 1989

Data Provided by:
Unique Michaud
(617) 825-9660
637 Washington St
Dorchester Center, MA
Specialty
Geriatric Medicine

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Daniel F Driscoll
(617) 364-4380
695 Truman Pkwy
Hyde Park, MA
Specialty
Geriatric Medicine

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Maria A Fiatarone
(781) 849-6476
1200 Centre St
Roslindale, MA
Specialty
Internal Medicine, Geriatric Medicine

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Food for Thought

Provided by: 

By Kris Kucera

Rarely does an extended family get a free pass from Alzheimer’s disease or diabetes mellitus. On the surface, these two afflictions appear totally unrelated —Alzheimer’s (AD), Mother Nature’s cruel version of identity theft; and diabetes, the glucose-metabolism disorder that affects both young and old alike. However, new research indicates that the two diseases behave in a similar manner.

In a study recently published in the Journal of Alzheimer’s Disease, researchers from Brown Medical School found that reduced glucose uptake and decreased metabolism in the hippocampus—the area of the brain associated with memory—cause neurodegeneration and cognitive impairment. This, they say, suggests that a form of diabetes, tentatively dubbed type 3, leads to AD.

Type 1 diabetes results from a severe or complete lack of insulin, a hormone made in the pancreas that controls blood sugar. Type 2, dubbed adult onset diabetes (although these days it occurs in teenagers and even younger kids), also stems from a dearth of insulin, or insulin resistance —the existing insulin molecules cannot deliver glucose through the cells’ membranes. Surprisingly, the researchers found a new form of insulin, produced in the brain, and they believe that, over time, decreasing levels of this “brain insulin” and other insulin-related proteins ultimately precipitate AD. While levels of brain insulin have no known affect on a body’s overall blood sugar, scientists have long recognized that diabetes patients are more likely to develop AD than those without the disease.

Skeptics of the Brown team’s findings argue that our brains produce so little insulin in the first place, reduced levels of the hormone can’t possibly play a significant role in AD. Regardless, the new data show that AD may be a neuroendocrine disorder, thus increasing the possibility for more effective treatments. And that gives hope to all of us who may one day be touched, directly or indirectly, by the merciless hand of AD.

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