Geriatric Healthcare Specialist Boston MA

In a study recently published in the Journal of Alzheimer’s Disease, researchers from Brown Medical School found that reduced glucose uptake and decreased metabolism in the hippocampus—the area of the brain associated with memory—cause neurodegeneration and cognitive impairment.

Ana Cecilia A Cury
(617) 724-0955
165 Cambridge St
Boston, MA
Specialty
Geriatric Medicine

Data Provided by:
Matthew Russell
(617) 638-6100
850 Harrison Ave
Boston, MA
Specialty
Internal Medicine, Geriatric Medicine

Data Provided by:
Kent Alan Creamer
(617) 248-1470
251 Causeway St
Boston, MA
Specialty
Internal Medicine, Geriatric Medicine

Data Provided by:
Randall Hutton McShine, MD
(617) 482-7555
885 Washington St
Boston, MA
Specialties
Geriatrics, Geriatric Medicine-Internal Medicine
Gender
Male
Education
Medical School: Univ Of West Indies, Fac Med Sci, Kingston, Jamaica (950-01 Pr 1/71)
Graduation Year: 1992

Data Provided by:
Jane Lucile Givens
(617) 638-6681
88 E Newton St
Boston, MA
Specialty
Geriatric Medicine

Data Provided by:
Kenneth Lloyd Minaker
(617) 726-4600
165 Cambridge St
Boston, MA
Specialty
Internal Medicine, Geriatric Medicine

Data Provided by:
Heidi P Auerbach
(617) 638-6100
850 Harrison Ave
Boston, MA
Specialty
Internal Medicine, Geriatric Medicine

Data Provided by:
Christopher M Coley
(617) 724-4600
15 Parkman St Wac 637
Boston, MA
Specialty
Internal Medicine, Geriatric Medicine

Data Provided by:
Eric J Hardt
(617) 638-6100
850 Harrison Ave
Boston, MA
Specialty
Geriatric Medicine

Data Provided by:
Erica D Bernstein
(617) 414-4639
850 Harrison Ave
Boston, MA
Specialty
Internal Medicine, Geriatric Medicine

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Food for Thought

Provided by: 

By Kris Kucera

Rarely does an extended family get a free pass from Alzheimer’s disease or diabetes mellitus. On the surface, these two afflictions appear totally unrelated —Alzheimer’s (AD), Mother Nature’s cruel version of identity theft; and diabetes, the glucose-metabolism disorder that affects both young and old alike. However, new research indicates that the two diseases behave in a similar manner.

In a study recently published in the Journal of Alzheimer’s Disease, researchers from Brown Medical School found that reduced glucose uptake and decreased metabolism in the hippocampus—the area of the brain associated with memory—cause neurodegeneration and cognitive impairment. This, they say, suggests that a form of diabetes, tentatively dubbed type 3, leads to AD.

Type 1 diabetes results from a severe or complete lack of insulin, a hormone made in the pancreas that controls blood sugar. Type 2, dubbed adult onset diabetes (although these days it occurs in teenagers and even younger kids), also stems from a dearth of insulin, or insulin resistance —the existing insulin molecules cannot deliver glucose through the cells’ membranes. Surprisingly, the researchers found a new form of insulin, produced in the brain, and they believe that, over time, decreasing levels of this “brain insulin” and other insulin-related proteins ultimately precipitate AD. While levels of brain insulin have no known affect on a body’s overall blood sugar, scientists have long recognized that diabetes patients are more likely to develop AD than those without the disease.

Skeptics of the Brown team’s findings argue that our brains produce so little insulin in the first place, reduced levels of the hormone can’t possibly play a significant role in AD. Regardless, the new data show that AD may be a neuroendocrine disorder, thus increasing the possibility for more effective treatments. And that gives hope to all of us who may one day be touched, directly or indirectly, by the merciless hand of AD.

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