Preeclampsia Treatment Towson MD

Researchers already knew that changes in the concentrations of two proteins—placental growth factor (PlGF) and soluble fms-like tyrosine kinase 1 (sFit1)—keyed the onset of milder forms of preeclampsia but did not seem to cause the life'threatening levels of high blood pressure seen in severe cases.

Frank J Bottiglieri MD
(410) 339-7640
6569 N Charles St
Towson, MD
Specialties
Obstetrics & Gynecology

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Francis Craig Grumbine, MD
(443) 849-2765
6569 N Charles St Ste 711
Towson, MD
Specialties
Oncology (Cancer), Gynecological Oncology, Gynecology
Gender
Male
Education
Medical School: Univ Of Va Sch Of Med, Charlottesville Va 22908
Graduation Year: 1974
Hospital
Hospital: Howard County General Hospital, Columbia, Md; Greater Baltimore Med Center, Baltimore, Md; St Joseph Hospital, Baltimore, Md; Johns Hopkins Hospital, Baltimore, Md

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Robert Edgar Ottenritter, MD
(410) 296-1364
6565 N Charles St Ste 212
Towson, MD
Specialties
Obstetrics & Gynecology
Gender
Male
Education
Medical School: Univ Auto De Guadalajara, Fac De Med, Guadalajara, Jalisco, Mexico
Graduation Year: 1982

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Richard Paul Marvel
(443) 632-0200
6569 N Charles St
Baltimore, MD
Specialty
Obstetrics & Gynecology

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Ruthann Theresa Zern, MD
(410) 339-7447
7505 Osler Dr Ste 402
Towson, MD
Specialties
Obstetrics & Gynecology
Gender
Female
Education
Medical School: Duke Univ Sch Of Med, Durham Nc 27710
Graduation Year: 1979

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John Yacoub, MD
(410) 321-7790
6565 N Charles St Ste 403
Towson, MD
Specialties
Obstetrics & Gynecology
Gender
Male
Education
Medical School: American Univ Of Beirut, Fac Of Med, Beirut, Lebanon
Graduation Year: 1982

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Robert H Solof
(410) 321-5460
7505 Osler Dr
Towson, MD
Specialty
Obstetrics & Gynecology

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W Scott Supplee, MD
(410) 821-7676
6569 N Charles St Ste 610
Towson, MD
Specialties
Obstetrics & Gynecology
Gender
Male
Education
Medical School: Univ Of Md Sch Of Med, Baltimore Md 21201
Graduation Year: 1986

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Dr.Ruthann Zern
(410) 339-7447
7505 Osler Dr # 402
Towson, MD
Gender
F
Education
Medical School: Duke Univ Sch Of Med
Year of Graduation: 1979
Speciality
Gynecologist (OBGYN)
General Information
Accepting New Patients: Yes
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4.5, out of 5 based on 12, reviews.

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Katherine M Bass, MD
(410) 296-6400
110 West Rd Ste 102
Baltimore, MD
Specialties
Obstetrics & Gynecology, Reproductive Endocrinology
Gender
Female
Education
Medical School: Duke Univ Sch Of Med, Durham Nc 27710
Graduation Year: 1983

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Early Warning Signs of Preeclampsia

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By Kathryn Ayers

High blood pressure, fluid retention, and excess protein in the urine all signal the onset of preeclampsia, a condition that affects one in 20 women during the third trimester of pregnancy. While a cause for concern in all cases—about 200,000 women suffer from preeclampsia in the US each year, and it is a leading cause of premature births—only those women who experience large and sudden increases in blood pressure face the threat of severe complications for themselves and their fetuses.

Researchers already knew that changes in the concentrations of two proteins—placental growth factor (PlGF) and soluble fms-like tyrosine kinase 1 (sFit1)—keyed the onset of milder forms of preeclampsia but did not seem to cause the life-threatening levels of high blood pressure seen in severe cases. Their new study in The New England Journal of Medicine names a third factor, soluble endoglin, that seems to kick preeclampsia into overdrive. This protein, which the researchers found in high concentrations in the placentas of women with severe preeclampsia, normally helps maintain the blood vessels, but when it sloughs off the blood vessel walls and combines with sFit1, it actually weakens them.

The study reports that soluble endoglin levels begin to increase markedly two to three months before the onset of preeclampsia and that this increase is usually accompanied by an increased ratio of sFit1 to PlGF. This forewarning should enable researchers to develop a diagnostic test that will allow healthcare providers to counter a major cause of maternal and fetal mortality worldwide.

Author: Kathryn Ayers

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