Preeclampsia Treatment Reading PA

Researchers already knew that changes in the concentrations of two proteins—placental growth factor (PlGF) and soluble fms-like tyrosine kinase 1 (sFit1)—keyed the onset of milder forms of preeclampsia but did not seem to cause the life'threatening levels of high blood pressure seen in severe cases.

Lorraine M Goodwin, MD
Reading, PA
Specialties
Obstetrics & Gynecology
Gender
Female
Education
Medical School: Univ Of Ca, San Francisco, Sch Of Med, San Francisco Ca 94143
Graduation Year: 1983

Data Provided by:
Nagi Helmi Abadier
(610) 378-2551
145 N 6th St
Reading, PA
Specialty
Obstetrics & Gynecology

Data Provided by:
Peter Alan Schwartz, MD
(610) 378-6827
6Th Avenue And Spruce St
Reading, PA
Specialties
Obstetrics & Gynecology
Gender
Male
Education
Medical School: Boston Univ Sch Of Med, Boston Ma 02118
Graduation Year: 1966
Hospital
Hospital: Reading Hosp & Med Ctr, West Reading, Pa
Group Practice: Reading Professional Svc

Data Provided by:
Gerald Malick
(610) 988-8446
6th Ave & Spruce St
West Reading, PA
Specialty
Obstetrics & Gynecology

Data Provided by:
Jeffrey Bruce Frank, MD
(610) 777-8600
1212 Liggett Ave
Reading, PA
Specialties
Obstetrics & Gynecology
Gender
Male
Education
Medical School: Univ Of Pa Sch Of Med, Philadelphia Pa 19104
Graduation Year: 1971

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Eli S Zinner
(610) 378-2570
145 N 6th St
Reading, PA
Specialty
Obstetrics & Gynecology

Data Provided by:
Ahlam N Khalil
(610) 764-1314
145 N 6th St
Reading, PA
Specialty
Obstetrics & Gynecology

Data Provided by:
George L Sexton
(610) 374-2214
301 S 7th Ave
West Reading, PA
Specialty
Obstetrics & Gynecology

Data Provided by:
Radhika Ailawadi
(610) 374-2214
301 S 7th Ave
West Reading, PA
Specialty
Obstetrics & Gynecology

Data Provided by:
Nabil Salim Muallem, MD
(610) 373-3738
301 S 7th Ave
West Reading, PA
Specialties
Obstetrics & Gynecology
Gender
Male
Education
Medical School: Univ Of Santo Tomas, Fac Of Med And Surg, Manila, Philippines
Graduation Year: 1980

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Early Warning Signs of Preeclampsia

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By Kathryn Ayers

High blood pressure, fluid retention, and excess protein in the urine all signal the onset of preeclampsia, a condition that affects one in 20 women during the third trimester of pregnancy. While a cause for concern in all cases—about 200,000 women suffer from preeclampsia in the US each year, and it is a leading cause of premature births—only those women who experience large and sudden increases in blood pressure face the threat of severe complications for themselves and their fetuses.

Researchers already knew that changes in the concentrations of two proteins—placental growth factor (PlGF) and soluble fms-like tyrosine kinase 1 (sFit1)—keyed the onset of milder forms of preeclampsia but did not seem to cause the life-threatening levels of high blood pressure seen in severe cases. Their new study in The New England Journal of Medicine names a third factor, soluble endoglin, that seems to kick preeclampsia into overdrive. This protein, which the researchers found in high concentrations in the placentas of women with severe preeclampsia, normally helps maintain the blood vessels, but when it sloughs off the blood vessel walls and combines with sFit1, it actually weakens them.

The study reports that soluble endoglin levels begin to increase markedly two to three months before the onset of preeclampsia and that this increase is usually accompanied by an increased ratio of sFit1 to PlGF. This forewarning should enable researchers to develop a diagnostic test that will allow healthcare providers to counter a major cause of maternal and fetal mortality worldwide.

Author: Kathryn Ayers

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