Preeclampsia Treatment Reading PA

Researchers already knew that changes in the concentrations of two proteins—placental growth factor (PlGF) and soluble fms-like tyrosine kinase 1 (sFit1)—keyed the onset of milder forms of preeclampsia but did not seem to cause the life'threatening levels of high blood pressure seen in severe cases.

Lorraine M Goodwin, MD
Reading, PA
Specialties
Obstetrics & Gynecology
Gender
Female
Education
Medical School: Univ Of Ca, San Francisco, Sch Of Med, San Francisco Ca 94143
Graduation Year: 1983

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Ahlam N Khalil
(610) 764-1314
145 N 6th St
Reading, PA
Specialty
Obstetrics & Gynecology

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George L Sexton
(610) 374-2214
301 S 7th Ave
West Reading, PA
Specialty
Obstetrics & Gynecology

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Saroj Parida
(610) 988-8843
6th Ave & Spruce St
West Reading, PA
Specialty
Neonatal-Perinatal Medicine

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Stacey G Ford
(610) 376-3700
740 Penn Ave
West Reading, PA
Specialty
Obstetrics & Gynecology

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Nagi Helmi Abadier
(610) 378-2551
145 N 6th St
Reading, PA
Specialty
Obstetrics & Gynecology

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Eli S Zinner
(610) 378-2570
145 N 6th St
Reading, PA
Specialty
Obstetrics & Gynecology

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Thomas Patrick Hanley, MD
(610) 375-4381
301 S 7th Ave
West Reading, PA
Specialties
Obstetrics & Gynecology
Gender
Male
Education
Medical School: St Louis Univ Sch Of Med, St Louis Mo 63104
Graduation Year: 1977
Hospital
Hospital: St Marys Health Center, Saint Louis, Mo; Missouri Baptist Med Ctr, Saint Louis, Mo; Forest Park Hosp, Saint Louis, Mo
Group Practice: Clayton Heights Ob/Gyn Associates

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Jeffrey C Zerby
(610) 370-2500
301 S 7th Ave
West Reading, PA
Specialty
Obstetrics & Gynecology

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Alexander Taylor Massengale
(610) 372-2800
301 S 7th Ave
West Reading, PA
Specialty
Obstetrics & Gynecology

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Early Warning Signs of Preeclampsia

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By Kathryn Ayers

High blood pressure, fluid retention, and excess protein in the urine all signal the onset of preeclampsia, a condition that affects one in 20 women during the third trimester of pregnancy. While a cause for concern in all cases—about 200,000 women suffer from preeclampsia in the US each year, and it is a leading cause of premature births—only those women who experience large and sudden increases in blood pressure face the threat of severe complications for themselves and their fetuses.

Researchers already knew that changes in the concentrations of two proteins—placental growth factor (PlGF) and soluble fms-like tyrosine kinase 1 (sFit1)—keyed the onset of milder forms of preeclampsia but did not seem to cause the life-threatening levels of high blood pressure seen in severe cases. Their new study in The New England Journal of Medicine names a third factor, soluble endoglin, that seems to kick preeclampsia into overdrive. This protein, which the researchers found in high concentrations in the placentas of women with severe preeclampsia, normally helps maintain the blood vessels, but when it sloughs off the blood vessel walls and combines with sFit1, it actually weakens them.

The study reports that soluble endoglin levels begin to increase markedly two to three months before the onset of preeclampsia and that this increase is usually accompanied by an increased ratio of sFit1 to PlGF. This forewarning should enable researchers to develop a diagnostic test that will allow healthcare providers to counter a major cause of maternal and fetal mortality worldwide.

Author: Kathryn Ayers

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