Preeclampsia Treatment Mcalester OK

Researchers already knew that changes in the concentrations of two proteins—placental growth factor (PlGF) and soluble fms-like tyrosine kinase 1 (sFit1)—keyed the onset of milder forms of preeclampsia but did not seem to cause the life'threatening levels of high blood pressure seen in severe cases.

R Ian Hardy, MD
(781) 237-0080
PO Box 908
McAlester, OK
Specialties
Obstetrics & Gynecology, Reproductive Endocrinology
Gender
Male
Education
Medical School: Univ Of Cincinnati Coll Of Med, Cincinnati Oh 45267
Graduation Year: 1988

Data Provided by:
Nelson Chukuka Onaro, DO
McAlester, OK
Specialties
Obstetrics & Gynecology
Gender
Male
Education
Medical School: Nova Se Univ, Coll Of Osteo Med, Ft Lauderdale Fl 33328
Graduation Year: 1992

Data Provided by:
Timothy Mark Cathey, MD
(405) 271-4060
1401 E Van Buren Ave
McAlester, OK
Specialties
Obstetrics & Gynecology
Gender
Male
Education
Medical School: Univ Of Ok Coll Of Med, Oklahoma City Ok 73190
Graduation Year: 1991
Hospital
Hospital: Mc Alester Regional Health Cen, McAlester, Ok
Group Practice: Acute Disease Svc

Data Provided by:
James Carl Manuele
(918) 426-0240
1401 E Van Buren Ave
Mcalester, OK
Specialty
Obstetrics & Gynecology

Data Provided by:
May-Li Barki, MD
(405) 755-7430
4140 W Memorial Rd
Oklahoma City, OK
Business
Center For Womens Health
Specialties
Obstetrics & Gynecology

Data Provided by:
James Carl Manuele Jr, MD
1401 E Van Buren Ave
McAlester, OK
Specialties
Obstetrics & Gynecology
Gender
Male
Education
Medical School: Creighton Univ Sch Of Med, Omaha Ne 68178
Graduation Year: 1997

Data Provided by:
Lonnie Dwain Doyle, MD
(918) 426-0240
4 E Clark Bass Blvd
McAlester, OK
Specialties
Obstetrics & Gynecology
Gender
Male
Education
Medical School: Baylor Coll Of Med, Houston Tx 77030
Graduation Year: 1978

Data Provided by:
Stephen J Riddel
(918) 426-0240
1401 E Van Buren Ave
Mcalester, OK
Specialty
Obstetrics & Gynecology

Data Provided by:
Marcia Ann Gillespie
(918) 426-7776
1125 Wade Watts Ave.
Mcalester, OK
Education
English
Professional Memberships
McAlester Regional Health Center

Guy W Sneed, DO
(918) 274-5555
12455 E 100th St N
Owasso, OK
Business
Owasso Womens Clinic
Specialties
Obstetrics & Gynecology

Data Provided by:
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Early Warning Signs of Preeclampsia

Provided by: 

By Kathryn Ayers

High blood pressure, fluid retention, and excess protein in the urine all signal the onset of preeclampsia, a condition that affects one in 20 women during the third trimester of pregnancy. While a cause for concern in all cases—about 200,000 women suffer from preeclampsia in the US each year, and it is a leading cause of premature births—only those women who experience large and sudden increases in blood pressure face the threat of severe complications for themselves and their fetuses.

Researchers already knew that changes in the concentrations of two proteins—placental growth factor (PlGF) and soluble fms-like tyrosine kinase 1 (sFit1)—keyed the onset of milder forms of preeclampsia but did not seem to cause the life-threatening levels of high blood pressure seen in severe cases. Their new study in The New England Journal of Medicine names a third factor, soluble endoglin, that seems to kick preeclampsia into overdrive. This protein, which the researchers found in high concentrations in the placentas of women with severe preeclampsia, normally helps maintain the blood vessels, but when it sloughs off the blood vessel walls and combines with sFit1, it actually weakens them.

The study reports that soluble endoglin levels begin to increase markedly two to three months before the onset of preeclampsia and that this increase is usually accompanied by an increased ratio of sFit1 to PlGF. This forewarning should enable researchers to develop a diagnostic test that will allow healthcare providers to counter a major cause of maternal and fetal mortality worldwide.

Author: Kathryn Ayers

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