Preeclampsia Treatment Grandview MO

Researchers already knew that changes in the concentrations of two proteins—placental growth factor (PlGF) and soluble fms-like tyrosine kinase 1 (sFit1)—keyed the onset of milder forms of preeclampsia but did not seem to cause the life'threatening levels of high blood pressure seen in severe cases.

E William Parker Jr, MD
(801) 756-5288
10301 Hickman Mills Dr
Kansas City, MO
Specialties
Obstetrics & Gynecology
Gender
Male
Education
Medical School: Univ Of Ut Sch Of Med, Salt Lake Cty Ut 84132
Graduation Year: 1974

Data Provided by:
Stephen Alan Myers, DO
(913) 588-6100
Overland Park, KS
Specialties
Obstetrics & Gynecology
Gender
Male
Education
Medical School: Philadelphia Coll Of Osteo Med, Philadelphia Pa 19131
Graduation Year: 1973

Data Provided by:
Leah D Ridgway, MD
(913) 677-3113
5721 W 119th St Ste 450
Overland Park, KS
Specialties
Obstetrics & Gynecology
Gender
Female
Education
Medical School: Baylor Coll Of Med, Houston Tx 77030
Graduation Year: 1988

Data Provided by:
Traci L Nauser
(913) 491-6878
4840 College Blvd
Overland Park, KS
Specialty
Obstetrics & Gynecology

Data Provided by:
Ronald Norman Yeomans, MD
4401 W 109th St
Overland Park, KS
Specialties
Obstetrics & Gynecology
Gender
Male
Education
Medical School: Univ Of Ks Sch Of Med, Kansas City Ks 66103
Graduation Year: 1967

Data Provided by:
Sharon Louise Binner, MD
Overland Park, KS
Specialties
Obstetrics & Gynecology
Gender
Female
Education
Medical School: Univ Of Ks Sch Of Med, Kansas City Ks 66103
Graduation Year: 1997

Data Provided by:
Gerald Ulysses Matile, MD
(816) 931-9344
11111 Nall Ave
Leawood, KS
Specialties
Obstetrics & Gynecology
Gender
Male
Education
Medical School: Univ Of Ks Sch Of Med, Kansas City Ks 66103
Graduation Year: 1982
Hospital
Hospital: St Lukes Hospital, Kansas City, Mo
Group Practice: Ferns Matile Smith & Perryman

Data Provided by:
Herbert C Hodes
(913) 491-6878
4840 College Blvd
Overland Park, KS
Specialty
Obstetrics & Gynecology

Data Provided by:
Bernard S Abrams, MD
(216) 621-5127
5520 College Blvd
Leawood, KS
Specialties
Obstetrics & Gynecology
Gender
Male
Education
Medical School: In Univ Sch Of Med, Indianapolis In 46202
Graduation Year: 1944

Data Provided by:
Karen R Cornwell
(816) 941-0700
1010 Carondelet Dr
Kansas City, MO
Specialty
Obstetrics & Gynecology

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Early Warning Signs of Preeclampsia

Provided by: 

By Kathryn Ayers

High blood pressure, fluid retention, and excess protein in the urine all signal the onset of preeclampsia, a condition that affects one in 20 women during the third trimester of pregnancy. While a cause for concern in all cases—about 200,000 women suffer from preeclampsia in the US each year, and it is a leading cause of premature births—only those women who experience large and sudden increases in blood pressure face the threat of severe complications for themselves and their fetuses.

Researchers already knew that changes in the concentrations of two proteins—placental growth factor (PlGF) and soluble fms-like tyrosine kinase 1 (sFit1)—keyed the onset of milder forms of preeclampsia but did not seem to cause the life-threatening levels of high blood pressure seen in severe cases. Their new study in The New England Journal of Medicine names a third factor, soluble endoglin, that seems to kick preeclampsia into overdrive. This protein, which the researchers found in high concentrations in the placentas of women with severe preeclampsia, normally helps maintain the blood vessels, but when it sloughs off the blood vessel walls and combines with sFit1, it actually weakens them.

The study reports that soluble endoglin levels begin to increase markedly two to three months before the onset of preeclampsia and that this increase is usually accompanied by an increased ratio of sFit1 to PlGF. This forewarning should enable researchers to develop a diagnostic test that will allow healthcare providers to counter a major cause of maternal and fetal mortality worldwide.

Author: Kathryn Ayers

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