Preeclampsia Treatment Bennington VT

Researchers already knew that changes in the concentrations of two proteins—placental growth factor (PlGF) and soluble fms-like tyrosine kinase 1 (sFit1)—keyed the onset of milder forms of preeclampsia but did not seem to cause the life'threatening levels of high blood pressure seen in severe cases.

Glen Carlisle Mackenzie, MD
160 Benmont Ave
Bennington, VT
Specialties
Obstetrics & Gynecology
Gender
Male
Education
Medical School: Loyola Univ Of Chicago Stritch Sch Of Med, Maywood Il 60153
Graduation Year: 1991

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Sarah Perkins Dahl
(802) 447-7591
345 Elm St
Bennington, VT
Specialty
Obstetrics & Gynecology

Data Provided by:
Denise Frances Poulin, MD
(518) 489-7439
194 North St
Bennington, VT
Specialties
Obstetrics & Gynecology
Gender
Female
Education
Medical School: Univ Of Vt Coll Of Med, Burlington Vt 05405
Graduation Year: 1984

Data Provided by:
Joan E Lister, MD
(413) 664-4343
197 Adams Rd
Williamstown, MA
Specialties
Obstetrics & Gynecology
Gender
Female
Education
Medical School: Tufts Univ Sch Of Med, Boston Ma 02111
Graduation Year: 1977

Data Provided by:
Bonnie H Herr
(413) 743-1263
2 Park St
Adams, MA
Specialty
Obstetrics & Gynecology

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John Matheson McLellan
(802) 442-8182
140 Hospital Dr
Bennington, VT
Specialty
Obstetrics & Gynecology

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John Matheson Mc Lellan, MD
(802) 442-8182
140 Hospital Dr Ste 305
Bennington, VT
Specialties
Obstetrics & Gynecology
Gender
Male
Education
Medical School: Mc Gill Univ, Fac Of Med, Montreal, Que, Canada
Graduation Year: 1968

Data Provided by:
Susan Jane Yates, MD
(413) 664-4343
197 Adams Rd
Williamstown, MA
Specialties
Obstetrics & Gynecology
Gender
Female
Education
Medical School: Mi State Univ Coll Of Human Med, East Lansing Mi 48824
Graduation Year: 1977

Data Provided by:
Ellen M Biggers, MD
(518) 677-2626
22 N Park St
Cambridge, NY
Specialties
Obstetrics & Gynecology
Gender
Female
Education
Medical School: Albany Med Coll, Albany Ny 12208
Graduation Year: 1987

Data Provided by:
Joan E Lister
(413) 743-1263
2 Park St
Adams, MA
Specialty
Obstetrics & Gynecology

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Early Warning Signs of Preeclampsia

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By Kathryn Ayers

High blood pressure, fluid retention, and excess protein in the urine all signal the onset of preeclampsia, a condition that affects one in 20 women during the third trimester of pregnancy. While a cause for concern in all cases—about 200,000 women suffer from preeclampsia in the US each year, and it is a leading cause of premature births—only those women who experience large and sudden increases in blood pressure face the threat of severe complications for themselves and their fetuses.

Researchers already knew that changes in the concentrations of two proteins—placental growth factor (PlGF) and soluble fms-like tyrosine kinase 1 (sFit1)—keyed the onset of milder forms of preeclampsia but did not seem to cause the life-threatening levels of high blood pressure seen in severe cases. Their new study in The New England Journal of Medicine names a third factor, soluble endoglin, that seems to kick preeclampsia into overdrive. This protein, which the researchers found in high concentrations in the placentas of women with severe preeclampsia, normally helps maintain the blood vessels, but when it sloughs off the blood vessel walls and combines with sFit1, it actually weakens them.

The study reports that soluble endoglin levels begin to increase markedly two to three months before the onset of preeclampsia and that this increase is usually accompanied by an increased ratio of sFit1 to PlGF. This forewarning should enable researchers to develop a diagnostic test that will allow healthcare providers to counter a major cause of maternal and fetal mortality worldwide.

Author: Kathryn Ayers

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